Try update Microsoft Defender and run a full system scan with it.
Try install all updates for Windows.
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Windows defender (MsMpEng.exe is consuming high CPU)
Any other suggestion, please.
Try update Microsoft Defender and run a full system scan with it.
Try install all updates for Windows.
Follow the steps on this page: https://learn.microsoft.com/en-us/defender-endpoint/tune-performance-defender-antivirus?view=o365-worldwide
Once you determine what file/process MsMpEng.exe is scanning, then you can determine what exclusions need to be set. Keep in mind that adding exclusions reduce your security posture.