@Steph (ZA-DUR), Welcome to Microsoft Q&A, based on my test, I reproduced the same problem. I could use the code to open a folder in .NET Framework but I meet the same error with you when used the code in .NET 6 app.
After checking the Microsoft Learning Process.Start Method, I find that there is no related description about the difference between .net frramework app and .net app.
However, I recommend that you could use the following method to open the folder without the exception.
string path = "C:\\Videos";
Process.Start(Environment.GetEnvironmentVariable("WINDIR") +
@"\explorer.exe", path);
Hope my solution could help you.
Best Regards,
Jack
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