Hi,
DPM can detect and protect VMs deployed on a VMware server (vCenter or ESXi server).
Unfortunately, I could not find any information about DPM 2022 backup for VMware 8.0. We may need to wait the newer version of DPM that supports VMware 8.0.
However, we can check out Microsoft’s DPM protection matrix for more information about what DPM can back up.
I hope this helps! Let me know if you have any other questions.