My best guess is that the memory leak report is being created before MFC object and other memory allocations have been freed.
Are you using global and or static objects? Are you creating objects on the heap and forgetting to destroy them?
Are you using functions that allocate memory and forgetting to free the allocation?
Without information about the code its difficult to provide specific guidance.
The path strings reported are not significant. It just indicates that the memory was allocated by MFC.
If there were inherent problems with MFC then all MFC users would be seeing these memory leaks reported in their debug builds.