Hi @Kazi Ariful Haq ,
Yes you can, you should perform the updates in a similar fashion as mentioned below:
1. Backup all databases.
2. Failover all SQL cluster roles to Node A.
3. Install the patches on Node B (passive).
4. Restart Node B.
5. Failover all SQL cluster roles to Node B.
6. Install the patches on Node A (passive).
7. Restart Node A.
You may also follow the official documentation over here:
Upgrade a failover cluster instance
https://learn.microsoft.com/en-us/sql/sql-server/failover-clusters/windows/upgrade-a-sql-server-failover-cluster-instance?view=sql-server-ver15
----------
(If the reply was helpful please don't forget to upvote or accept as answer, thank you)
Best regards,
Leon