Hi @Jeff X,
How can I use those app alongside IIS if IIS will also listens on those IP's?
If you have IIS installed and want to manage listening on specific IP addresses through it, you can host the applications on IIS first and then bind IP addresses to them. Just refer to this doc: Create and Configure an IIS Website. Something like this：
Why do I have to run those commands if ISS is not installed?
Because in your current case, since you haven't installed IIS, IIS is not using those IP addresses that you added with the "netsh http add iplisten" command. They are configured specifically for the HTTP service that your web applications use to listen on the specified IP address.
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