Hello George Quevin ,
Welcome to the MS Q&A platform.
Did you get a chance to look into the Data Provider Error Codes document?
can you please test whether you can connect to DB2 from the SHIR machine using the same connection string?
Can you please test the linked service connection using the ODBC link service? https://docs.microsoft.com/en-us/azure/data-factory/connector-odbc.
Please let me know if you have any further questions.