Hello there,
I would suggest you have a quick look on the Recommended settings for VDI desktops and tune your settings in your environment based on this article https://learn.microsoft.com/en-us/windows-server/remote/remote-desktop-services/rds-vdi-recommendations
Try temporarily disabling your antivirus software or any other app that might scan your device during sign-in.
If you continue to experience issues signing in with your original profile, disable Windows Defender services: Open the Services app by typing services in the search box on the task bar and selecting it from the list of results. Then, find the Windows Defender Advanced Threat Protection and Microsoft Defender Antivirus services, right-click each of them, select Properties, and change Startup Type to Disabled, selecting OK after each change. Restart your device in normal mode and try to sign in with your original profile. (Note: After troubleshooting and resolving the issue, remember to set the Windows Defender services back to Automatic.)
Hope this resolves your Query !!
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