
Hi @Damon Norris,
Thank you for posting in this community.
I would like to confirm your question to you: you want to set up a FQDN to SharePoint2016 and then SharePoint2016 can link to Office Online Server so that external users can access the Office Online Server through Share Point2016, do I understand correctly?
I noticed that you mentioned in your question about configuring on a F5 load balancerIf you still need to use a F5 load balancer for configuration, I suggest you go to F5 load balancer community for more help.
For SharePoint, we can configure Office Online Server for SharePoint Server.
This is the article on configuration: Configure Office Online Server for SharePoint Server. You can see if you can use it as an alternative.
Thank you for your kind understanding.
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