Hello,
Usually the main reason for serial port communication issues can be fixed with the next checklist:
- Check if the cable is in good condition and it follows the manufacturer standards (some manufacturers would change some of the I/O routing)
- Check the setting for the connection on the connection tool (MobaXterm, but you can try with PuTTy as well) such as baud rate, data bits, parity, stop bits, etc.
- Check for conflict with other ports such as DMA or IRQ that would prevent the communication
- Ensure that drivers for both COM ports and device are successfully installed
- Temporary disable or check for setup of your anti-malware or firewall as they could be blocking the COM connections
Hope this resolves your Query !!
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