Issue reaching logic app host

Question

For the last week we have been experiencing some issues reaching a logic app host.

We use logic apps in our subscription, and the endpoints are backed by a pool of IPs.

One in particular is often raising this error

System.Net.Http.HttpRequestException: An error occurred while sending the request. ---> System.Net.WebException: Unable to connect to the remote server ---> System.Net.Sockets.SocketException: A connection attempt failed because the connected party did not properly respond after a period of time, or established connection failed because connected host has failed to respond 20.103.21.113:443

Is there a way to have this checked by MS?

Thanks

Michele