Rafael Barrameda---there are many solutions to your problem but it depends on what you are expecting.
1. If you want to get more space by combining drives C: and E: without data loss then you can use a software called Partition Magic, which helps to resize your partition without any data loss. https://www.partition-magic-server.com/help/merge-partition.html
2. If you want to keep drive E: as it is and only like to get more space on drive C: then you have the following choices:
A. Get a partition cloning tool like macrium reflect https://www.macrium.com/reflectfree
and do the image backup of your drive C: to drive E: and then upgrade the physical drive of your PC to higher capacity (preferably 256 GB or more) and then restore the image file to the new drive. However, during restoration you need to select the maximum size to the whole size of the new drive. This will bring everything back to how it was before with additional free space.
B. You can only backup the selected folders to drive E: and then format drive C: and reinstall the OS. But this will take a lot of time and you should know to install OS and drivers on a PC.
3. Uninstall the programs that are taking more space and you can do that using the Revo uninstaller https://www.revouninstaller.com/. This app will show the list of apps installed on your computer and you can also see the amount of space taken by each app.
I think option 1 and 3 would be easier for you but if you don't want to struggle with these then simply copy the data from your user folder to drive E: but you didn't show which folders within your user directory is taking more space. If it's the Desktop folder then you need to copy the larger files from your desktop to drive E: and then delete the files from your desktop. However, you also need to empty your recycle bin finally to get the free space. You can also try disk cleaners like Windows Disk Clean Utility and other third-party disk cleaners to clean temporary files. This will also free up some of your space and can make your PC run faster.
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