Azure App Service is a service used to create and deploy scalable, mission-critical web apps.
@WinTechie Give below code a try--it's what I've been testing with:
$webapp = Get-AzResource -Name mywebapp -ResourceGroupName myresourcegroup -ResourceType Microsoft.Web/sites
$webapp.Properties.siteConfig.minTlsCipherSuite = "TLS_ECDHE_RSA_WITH_AES_256_GCM_SHA384"
$webapp|Set-AzResource -Force