Posts about SSMS misbehaving are certainly not uncommon in these forums. However, these symptoms are nothing that I recognise.
I can't say have much ideas for any of them. What I would try with the OE case is to start up Profiler with a filter to capture what SSMS emits. Then I would right-click on the Database node or which other node that is empty and select Refresh. Does SSMS run a query? Not I am sure what we would do with this information in either case.
As for the settings file, are you running some antivirus (other than Windows Defender) or some other "special" software? The symptoms does sort of suggest a conflict with some other program.