Exxchange Server 2019 is supported as an Azure-VM as long as all supportability requirements are met. => see Note
Deployment of Exchange 2016 or Exchange 2019 on Infrastructure-as-a-Service (IaaS) providers is supported if all supportability requirements are met. In the case of providers who are provisioning virtual machines, these requirements include ensuring that the hypervisor being used for Exchange virtual machines is fully supported, and that the infrastructure to be utilized by Exchange meets the performance requirements that were determined during the sizing process. Deployment on Microsoft Azure virtual machines is supported if all storage volumes used for Exchange databases and database transaction logs (including transport databases) are configured for Azure Premium Storage.
Decision to implement a DAG (Database Availability Group) with IP-based vs IP-less configurations depends on various factors (organization's specific requirements, infrastructure, and operational preferences)
Pros for each:
- IP-Based DAG
- Granular Control: IP-based DAG provides more granular control over which databases and network interfaces are used for replication and failover. You can configure specific IP addresses for each database copy.
- Isolation:Each database copy has its own dedicated IP address, which can help isolate issues if one database copy experiences problems. This can simplify troubleshooting.
- Complex Network Configurations: If your network environment is complex, with multiple subnets, routing rules, or specific network requirements, an IP-based DAG can provide more flexibility in handling these scenarios.
- Custom Routing: You can use routing rules to control how replication traffic flows, which can be useful in scenarios where you want to optimize network utilization or prioritize certain traffic.
- Complex Network Configurations: If your network environment is complex, with multiple subnets, routing rules, or specific network requirements, an IP-based DAG can provide more flexibility in handling these scenarios.
- Isolation:Each database copy has its own dedicated IP address, which can help isolate issues if one database copy experiences problems. This can simplify troubleshooting.
- Granular Control: IP-based DAG provides more granular control over which databases and network interfaces are used for replication and failover. You can configure specific IP addresses for each database copy.
- IP-Less DAG
- Simplified Configuration: IP-less DAG configurations simplify the overall configuration and reduce the number of IP addresses required. This can make the setup process more straightforward.
- Reduced IP Address Management: You don't need to manage as many IP addresses, which can reduce the administrative overhead associated with IP management, especially in larger environments.
- Ease of Scaling: IP-less DAGs can be easier to scale because you don't have to allocate and manage additional IP addresses for each new database copy.
- Smaller Attack Surface: With fewer IP addresses exposed, there may be a smaller attack surface, potentially enhancing security.
- Ease of Scaling: IP-less DAGs can be easier to scale because you don't have to allocate and manage additional IP addresses for each new database copy.
- Reduced IP Address Management: You don't need to manage as many IP addresses, which can reduce the administrative overhead associated with IP management, especially in larger environments.
- Simplified Configuration: IP-less DAG configurations simplify the overall configuration and reduce the number of IP addresses required. This can make the setup process more straightforward.
In general
- IP-less will be easier to set-up and manage for a smaller organization
- IP-based DAGs will allow for complex network requirements, allow more control and specific isolation requirements that suit larger enterprises.
And do check for support of your scenario with 3rd party providers like backup, ... (especialy about Administrative Access Point=AAP).
Afaik when you choose your architecture, you must stick with it, else create a new DAG.
So the answer is 'it depends' on your objectives.
You can read about Exchange 2019 preferred architecture here: https://learn.microsoft.com/en-us/exchange/plan-and-deploy/deployment-ref/preferred-architecture-2019?view=exchserver-2019
An rather old post regarding your question is here: https://social.technet.microsoft.com/wiki/contents/articles/48850.exchange-2013-ip-less-dag-vs-dag-with-ip.aspx
Regards