Hi @ComputerHabit ,
Are you running Application Guard in Standalone mode? First, you can try to check if you have met all the System requirements. Second, you can refer to this FAQ to see if it can fix the issue.
If issue persists, it's may be related with your local environment and need complex troubleshooting, I suggest that you can open an assisted support ticket so that you can get more help.
Thanks for your understanding.
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Regards,
Wenying Lu