Hi,
To the best of my knowledge, it's NOT suggested to restrict the network traffic between any internal Exchange servers. And according to the ground rule in the following official document, if you have firewalls that may restrict the network traffic, you'll need to configure rules that allow free and unrestricted communication between these servers:
Network ports for clients and mail flow in Exchange
Moreover, the blog below also mentions that "a rule allowing 'ANY/ANY' port and protocol communication must be in place allowing free communication between Exchange servers as well as between Exchange servers and domain controllers":
Exchange, Firewalls, and Support… Oh, my!
Hope you can find the above information helpful.
If an Answer is helpful, please click "Accept Answer" and upvote it.
Note: Please follow the steps in our documentation to enable e-mail notifications if you want to receive the related email notification for this thread.