Hello @Ben McFadden ,
Thanks for reaching out to Microsoft Q and A platform.
I understand that you unable to Access the Spoke Vnet from on premise, could you please verify the following steps?
- Please check the NSG of the incoming traffic on the Spoke Vnet or the VM. They must allow your on-premise.
- Try to enable the Psping from on premise to spoke VM, this error message would give you more about the reachability.
- Make sure to Add the Route to the Spoke Vnets on the On-premise side, so that it knows where to forward the traffic when reach the Spoke.
- Please do analyze the Effective Routes on the Spoke VM NIC, which would confirm what route it takes for the On-premise Address Range.
- If these routes are configured correctly, then your troubleshooting must be with On-premise Firewall and Route.
Regards, Priya Kumar.