Hi @Joe Grover
For message subject you can use regax ^$ to match an empty string.
Create a transport rule like:
While based on my test it may not work for the message body, as message body may contain other characters or elements although the message body seems to be empty.
If the answer is helpful, please click "Accept Answer" and kindly upvote it. If you have extra questions about this answer, please click "Comment". Note: Please follow the steps in our documentation to enable e-mail notifications if you want to receive the related email notification for this thread.