Hello Andy Forbes,
Thank you for posting in Q&A forum.
Are both the two DCs also DNS servers? If so, you can install DNS role on both DCs. And make both DCs point towards each other from the start, with secondary being themselves.
Then run commands ipconfig /flushdns and ipconfig /registerdns on both Domain Controllers.
Here is a similar thread for your reference.
https://community.spiceworks.com/topic/2198336-winserver-2016-seeing-replication-errors-in-ad-dc-dont-know-how-to-resolve?page=1#entry-8278239
Here is a link to troubleshoot the event ID 1753.
https://learn.microsoft.com/en-us/windows-server/identity/ad-ds/manage/replication-error-1753-there-are-no-more-endpoints-available-from-the-endpoint-mapper
I hope the information above is helpful. If you have any questions or concerns, please feel free to let us know. Best Regards, Daisy Zhou
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