You really haven't provided us any context as to what you're trying to do such that this error occurs. Are you trying to open a solution in VS, compile your code, run your app, what?
Just off the top of my head it looks like a VS issue opening the designer. In that case try closing the designer and reopening it. If this is a VS issue then please also confirm the version of VS you're using, What designer (if any) you're trying to load, and whether you have the async solution load option set (in options).