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Hi @Guerrero, Darlene (EXTERNAL),
You may have a look at the policy NewPDFReaderEnabled, which enables the Adobe Acrobat powered PDF reader engine in Microsoft Edge. Since your hyperlink works in Adobe Reader, there's a chance to do the same thing with this policy.
You can understand that it is related to Chromium Embedded Framework features, but you can request for new features, too. To request a feature, please send feedback to the Edge Dev Team by Alt+Shift+I.
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Best Regards,
Shijie Li