Hi @Darryl Hoar ,
Be sure to also check the Prerequisite for the setup project property to make sure it also has Microsoft .NET Framework 4.5.2 selected.
After you've checked that the project goal framework matches the Prerequisite and startup conditions, if the warning persists, try cleaning the solution and then rebuilding it.
Best Regards.
Jiachen Li
If the answer is helpful, please click "Accept Answer" and upvote it.
Note: Please follow the steps in our documentation to enable e-mail notifications if you want to receive the related email notification for this thread.