
any Help !!
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Now plan deploy MDE my PC joins local AD which makes it difficult to manage policy through GPO. Is this possible? If I want to use Switch Gpo policy through Device configuration management MDE?
It not very clear what you are requesting but from my understanding, below is your scenario:
Yes, this is possible. Here is a step-by-step guide on how to achieve this. https://learn.microsoft.com/en-us/defender-endpoint/configure-endpoints-gp?view=o365-worldwide