Please tell me the version of your Office.
Open an Office application, File>Account>About…
Is there any error message when the files cannot be opened?
If there is, please give the screenshot.
Apart from Office files, does this cross sign appear on other icons like software shortcuts?
Besides, have these files been synced with OneDrive before?
There may be something wrong with OneDrive sync.
Please sign in to OneDrive again to have a check.
If you have any updates, please post back.
Regards,
Erin
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