I suggest you try following steps to have a check:
- Check Office version number Open Word, click File > Account, check the version number under Product Information. Please try to update Office to the newest one.
- Check where the file is saved I suggest you change the location to save your file. For example: if you want to save files to OneDrive online, you may save files to local folders.
- Check default printer Click Windows Start menu > Settings > Devices > Printers & scanners > select a printer > Manage. Then select another one as the default, such as "Microsoft Print to PDF".
- Run Word in safe mode to test You can press and hold on Ctrl key, click or double-click Word icon, until Word asks do you want to start it in safe mode, then please release Ctrl key and click "Yes". Then Create a new blank document and try to save it.
Any updates or further issues, welcome to post back.
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