Please check if all necessary profiles were successfully deployed according to Deploy Microsoft Defender for Endpoint on macOS with Microsoft Intune
Full Disk Access - https://learn.microsoft.com/en-us/defender-endpoint/mac-install-with-intune#step-3-full-disk-access
If Intune shows that the profile was successfully installed you can verify it manually.
To grant full disk access:
Open System Preferences > Security & Privacy > Privacy > Full Disk Access. Click the lock icon to make changes (bottom of the dialog box).
- Grant Full Disk Access permission to Microsoft Defender and Microsoft Defenders Endpoint Security Extension.
- Select General > Restart for the new system extensions to take effect.
To check device issues, refer to Troubleshoot cloud connectivity issues for Microsoft Defender for Endpoint on macOS
Best regards,
Aleksandr
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