@Francesco Russo - Thanks for the question and using MS Q&A platform.
The Microsoft Purview Data Map supports automatic labeling only. Labels are automatically applied to assets in the data map based on the classifications found on the assets and the autolabeling rules for the labels.
The Microsoft Purview Data Map doesn't currently support manually applying a label, modifying, or removing a label from an asset.
For more details, refer to How to automatically apply sensitivity labels to your data in the Microsoft Purview Data Map (Preview).
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