Hello,
Thank you for posting in Microsoft Community forum.
Based on the description, I understand your question is related to upgrade win 10 LTSC.
Yes, according to Microsoft document, upgrade from Windows LTSC to Windows General Availability Channel is available when upgrading to the same or a newer build version.
For example, Windows 10 Enterprise 2016 LTSB can be upgraded to Windows 10 Enterprise 22H2. Upgrade is supported using the in-place upgrade process using Windows setup.
The Product Key switch needs to be used if apps need to be kept. If the switch isn't used, the option Keep personal files and apps option is grayed out. The command line to perform the upgrade is:
setup.exe /pkey xxxxx-xxxxx-xxxxx-xxxxx-xxxxx
where xxxxx-xxxxx-xxxxx-xxxxx-xxxxx is the Windows General Availability Channel product key.
reference link:
Windows upgrade paths | Microsoft Learn
Have a nice day.
Best Regards,
Molly