Hello Gergely Szabó1,
Thank you for posting in Microsoft Community forum.
The reason why Remote Credential Guard stops working when you change the client GPO setting to "Restrict Credential Delegation" is that this setting restricts the delegation of user credentials to remote servers. This means that the client will not be able to delegate the user's credentials to the remote server, which is required for Remote Credential Guard to work.
When you enable the "Require Remote Credential Guard" setting, it ensures that the client uses Remote Credential Guard to protect the user's credentials when they are being delegated to the remote server. However, if you enable the "Restrict Credential Delegation" setting, it overrides the "Require Remote Credential Guard" setting and prevents the client from delegating the user's credentials to the remote server.
Therefore, to use Remote Credential Guard, you need to ensure that the "Restrict Credential Delegation" setting is not enabled on the client.
I hope the information above is helpful.
If you have any question or concern, please feel free to let us know.
Best Regards,
Haijian Shan