Hello, @Marc Müllenbach
Welcome to the Microsoft Q&A platform!
In an Exchange Online hybrid scenario, if you configure multiple smart hosts in the outbound connector, they are used in a round robin fashion by default. This means that Exchange Online will distribute outbound emails evenly across all the configured smart hosts.
If you want to implement failover (where one smart host is used primarily and the others are used only if the primary one fails), you will need to set up more sophisticated load balancing and failover mechanisms outside of the standard Exchange Online configuration options. You might achieve this using a load balancer or by configuring DNS with multiple MX records with different priorities, but Exchange Online itself will use round robin for multiple smart hosts specified directly in the outbound connector.
If the answer is helpful, please click on “Accept answer” as it could help other members of the Microsoft Q&A community who have similar questions and are looking for solutions.
Thank you for your support and understanding.
Best Wishes,
Alex Zhang