Please give two screenshots of the detailed error message and Office version.
You could go to File>Account>About Excel to check the version.
Does this issue occur on specific Excel file or all files?
If specific Excel file, is there any code in it?
Please check if code is incompatible with the version or architecture of this application (for example, code in a document targets 32-bit Microsoft Office applications but it is attempting to run on 64-bit Office).
You could try to open Excel in safe mode to eliminate interference from add-ins and startup items.
Press Windows+R, type excel /safe, click OK.
If nothing is wrong when opening Excel in safe mode:
- Move the files in C:\Users\<User Name>\AppData\Roaming\Microsoft\Excel\XLSTART to other location temporarily, then check if the issue still exists.
- If it doesn't work, please go to File>Options>Add-Ins. Towards the bottom of the window, where it says Manage, select COM Add-ins, click Go. In the dialog box, uncheck the add-ins to disable them.
Then close and restart Excel to see if the issue is resolved.
If safe mode doesn’t help, you could repair Office online.
Besides, you could also try to clear all the files in C:\Users\<User Name>\AppData\Roaming\Microsoft\Excel to check this issue.
Note: please back up important files before clearing them.
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