Hi ]chris[
Thank you for posting in Microsoft Community.
I understand the frustration you are experiencing with default apps resetting on your Windows 10 system. Since you have already tried several troubleshooting steps without success, let's focus on resolving the issue related to PDFs and default apps.
> Disable Microsoft’s Default App Reset Behavior
Windows sometimes forces default apps back to Microsoft programs after updates. You can try disabling this behavior:
Open Registry Editor (Win + R > type regedit).
Navigate to:
HKEY_LOCAL_MACHINE\SOFTWARE\Policies\Microsoft\Windows\Explorer
If Explorer doesn’t exist, create it.
Inside Explorer, create a DWORD (32-bit) Value named:
NoOpenWith
Set its value to 1.
Restart your PC and check if your default apps persist.
> Prevent Windows from Resetting Defaults via Group Policy
If you're using Windows 10 Pro, you can try this:
Open Group Policy Editor (Win + R > type gpedit.msc).
Navigate to:
Computer Configuration > Administrative Templates > System > Default Associations Configuration
Enable "Turn off Microsoft Default Associations".
Restart your PC.
> Lock Default Apps via Registry
Since modifying the registry for Edge hijacking PDFs didn’t work, try locking your default apps:
Open Registry Editor and go to:
HKEY_CURRENT_USER\Software\Microsoft\Windows\CurrentVersion\Explorer\FileExts.pdf\UserChoice
Delete the UserChoice key.
Restart your PC and manually set Acrobat as the default again.
> Create a New User Profile
If your current profile is corrupted, Windows may not retain default app settings:
Open Settings > Accounts > Family & Other Users.
Create a new local user account.
Log into the new account and set default apps.
Restart and check if they persist.
Open Command Prompt (Admin) and run:
dism /online /Import-DefaultAppAssociations:C:\Path\To\DefaultApps.xml
Restart your PC.
Perform Repair in-place upgrade: This will reinstall your Operating System and will keep your files and apps. This will take some time depending on the computer performance and internet speed. You can follow the steps from this link: How to do a Windows 10 Repair Upgrade - Microsoft Community
Please let me know if this helps
Best Regards,
Lonex P.
Microsoft Moderator