You are asking in a Windows Vista group. Post in a Windows 7 group. Tell them what you have already tried and exactly what happened.
http://answers.microsoft.com/en-us/windows/forum/windows_7?tab=all
Module Name: spldr
Display Name: Security Processor Loader Driver
Description: Security Processor Loader Driver
Driver Type: Kernel
Start Mode: Boot
State: Running
Status: OK
Accept Stop: TRUE
Accept Pause: FALSE
Paged Pool(bytes): 4,096
Code(bytes): 4,096
BSS(bytes): 0
Link Date: 26/10/2006 9:40:44 AM
Path: C:\Windows\system32\drivers\spldr.sys
Init(bytes): 4,096
Try checking for corrupted files.
SFC
Check for file corruption by clicking Start - All Programs - Accessories - Right click
Command Prompt and choose Run As Administrator. Type (or copy and paste by right clicking in the Command Prompt window and choosing
Paste).
sfc /scannow
For SFC Results
Start - All Programs - Accessories - Right click Command Prompt and choose
Run As Administrator. Type (or copy and paste by right clicking in the Command Prompt window and choosing
Paste).
findstr /c:"[SR] Cannot" %windir%\logs\cbs\cbs.log|more
This will see which files are corrupted
Then try to start the driver and see what error happens.
Start - All Programs - Accessories - Right click Command Prompt and choose
Run As Administrator. Type (or copy and paste by right clicking in the Command Prompt window and choosing
Paste).
sc start spldr
If it works in safe mode try clean boot troubleshooting.
Each of the two steps turns of programs, services, and drivers in increasing amounts. Thus narrowing down the possible culprits.
Clean Boot
Click Start - All Programs - Accessories- Run and type
msconfig
Then go to the Startup tab. Untick everything. Then go to the
Services tab. Tick Hide All Microsoft Services and untick everything that's left.
Reboot. If this solves your problem reenable ½ of the services/startup items until you find which one.
Advanced Clean Boot
If the above doesn't help.
Download Autoruns from http://technet.microsoft.com/en-us/sysinternals/bb963902.aspx
Start the program by right clicking and choosing Run As Administrator and click
Options menu - Filter Options and tick Hide Microsoft entries and clear
Include Empty Locations. Untick everything left.
Reboot. If this solves your problem reenable ½ of the items until you find which one.