Hi @shankar431 ,
yes, you can, but you need to enable some auditing related GPO settings, so that the access to those files and folders is logged in the form of events.
You can find a very nice example here that will also work for SCOM 2012 R2 of course:
Monitoring File Access with SCOM
You can also check the Asnwer of Leon from the old Social Technet forums:
The following post froms the SquaredUp forums is presenting also another approach (script based):
Monitor a Folder in FileServer for User Addition/Removal
Hope this will help you out!
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