Hi Eric,
The startup programs will only launch once an account has already been logged in (when you log in and your profile loads). It could be possible that the account that you use is already running before your wife logged in to the computer, having 2 active logins on the computer. Can you verify if the issue occurs if the issue occurs when only your wife's account was logged in after a complete restart of the computer? I don't have any data on Steelseries Engine, so I'm not sure if it has any control on any other startup process your profile has.
A good method to isolate the issue even further is to perform a clean boot on your profile temporarily, then test if the issue occurs on the other account. Do ensure that you restart the computer normally after troubleshooting. The instructions are also included in the article.
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