Probably one or more extensions causing the slowdown. Run VS in safemode. If the problem goes away it is an extension issue. In newer VS versions it should report if an extension is slowing things down too much. Otherwise you'll need to start disabling your extensions until the problem goes away. Once you've found the extension you can report the issue to the author.
Alternatively you can use Report a Problem in VS directly, replicate the issue and send the report to MS so they can look at it. From there they will either identify an issue in the shell or be able to identify which extension is causing the slowdown.
