Windows 2016 server does support Microsoft Access Database Engine 2016.
Does windows 2016 server support Microsoft Access Database Engine 2016 Redistributable

In order to read the XLSX files I planned to install AccessDatabaseEngine_x64.exe available at: https://www.microsoft.com/en-us/download/details.aspx?id=54920 I realized however that Windows 2016 Server is not listed in the <System Requirements> section. The last version supported is Windows Server 2012 R2. Where can I find the ODBC driver which enables my C# applications to read Excel files safely at Windows Server 2016 ?
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Castorix31 71,621 Reputation points
2021-03-03T14:36:20.65+00:00 I don't know for Microsoft Access Database Engine on Windows Server 2016, but you could also use Open XML SDK to read/write .XLSX
From requirements (What's new in the Open XML SDK 2.5 for Office), there is :"Open XML SDK 2.5 requires .NET Framework 4.0 or the greater version. Accordingly, the supported operating systems are updated to be the same as the requirements of the .NET Framework 4.0."
So it should work on Windows Server 2016 as .NET Framework 4.6.2 is installed by default (Supported server operating systems)