Hi @Muhammed Shehim ,
What's the version of your Exchange server?
Any changes were made to your Exchange environment before this issue occurred?
Please go to Event Viewer and see if there are any relevant events?
Besides, it's suggested to check the Exchange Back End website bindings via IIS manager > Exchange Back End, right click and choose Bindings, highlight https and click Edit, make sure a proper certificate is bound to the site:
Furthermore, please have a look at the authentication settings of Powershell in both the Default Web Site and the Exchange Back End, see if they are same as the default settings:
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