@Vicki F
Thanks for your reply and sharing.
Are you using multiple displays?
If there is a multi-monitor setup with a huge difference in screen resolutions, it may cause the display issues like yours.
For more detailed information, you may refer to the article "Office support for high definition displays".
Please check this issue after switching back the option of "Optimize for best appearance".
If this issue goes away, please accept the answer for cooldadtx's reply, this action would help other forum users who have the similar issues and read this thread.
Thanks for your understanding.
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