Hi @Susan Dodds
Refer to the below thread discussed the similar issue best practice for Exchange installation path:
Recommendation for Exchange 2016 default installation path
Intalling on C or on a separate disk are both supported. Make sure you have meet the Exchange Server system requirements
And Database Log File Best Practices / Microsoft Recommended Configuration
Exchange Server 2016: Data and log files location
The official document here introduces about Best practices for supported storage configurations
Mailbox database and log volume co-location are not recommended in standalone architectures. In high availability architectures, there are two possibilities for this scenario:
- Single database per volume
- Multiple databases per volume
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