@tarou chabi Thanks for posting in our Q&A. From your description, I know that you want to prevent users from removing management profile in iOS devices. If there is anything misunderstanding, feel free to let us know.
For this issue, I have done a lot of research. In our official atricle, it seems only ADE supports lock down the management profile.
https://learn.microsoft.com/en-us/mem/intune/enrollment/device-enrollment#iosipados-enrollment-methods
At the same time, I find that someone has post the same question in the Apple forum. In this post, it provided a method that create a password protected profile in Apple Configuation.
https://discussions.apple.com/thread/7275348
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