Hello @Praveen Poulose ,
Thank you for posting here.
Based on the description, I understand if the machine is not connected to domain network, the startup apps, office application and other software work fine.
And if the machine is connected to domain network:
if you log on this machine with local account (local Administrator account or normal local user account), the startup apps, office application and other software work fine,
but if you log on this machine with domain user account (domain Administrator account or normal domain user account), the startup apps, office application and other software will not work, is it right?
If so, it seems there is domain policy (user configuration) caused this issue.
We can find one machine with the issue in the domain and troubleshoot as below:
1.Logon machine in the domain using domain account.
2.Create one folder in C drive (such as C:\folder1).
3.Open CMD (do not run as administrator).
4.Type gpresult /h C:\folder1\report1.html and click Enter.
5.Open report2.html and check GPO settings under "User Details".
1.Logon machine in the domain using local account.
2.Create one folder in C drive (such as C:\folder2).
3.Open CMD (do not run as administrator).
4.Type gpresult /h C:\folder2\report2.html and click Enter.
5.Open report2.html and check GPO settings under "User Details".
At last, compare GPO settings under "User Details" for working case and non-working case.
Would you please tell us the error message when you open the startup apps, office application and other software and they do not open?
Hope the information above is helpful.
Should you have any question or concern, please feel free to let us know.
Best Regards,
Daisy Zhou
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