@fra.pc
Hi,
As far as I know, the default protected folders include Windows system files and the built-in, common default document and content folders.
I'm afraid you can't modify the default allowed programs. That's by design, to protect your operating system from something malicious that tries to do the same thing.
Please refer to the following information:
Controlled folder access applies to many system folders and default locations, including folders such as Documents, Pictures, and Movies. You can add other folders to be protected, but you cannot remove the default folders in the default list.
https://learn.microsoft.com/en-us/microsoft-365/security/defender-endpoint/customize-controlled-folders?view=o365-worldwide
For folder located on a sleeping drive, there is no clear information, but you can check the Windows event logs under the Windows Defender source to verify it.
Hope above information can help you.
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