Hello Dr0wnedZephyr,
Welcome to Microsoft Community.
Let me first explain to you what memory integrity protection is and how it works.
Memory Integrity helps prevent attackers from injecting their own malicious code and helps ensure that all drivers loaded onto the OS are signed and trustworthy.
This is a feature that provides greater protection for Windows systems in general, when memory integrity protection is enabled, the system scans all drivers and applications in the device to ensure that they have the correct signatures and certificates.
Enable virtualization-based protection of code integrity
Options to Optimize Gaming Performance in Windows 11
However, considering that individual users may inevitably use some applications or drivers that do not contain signatures or expired certificates in daily use, if this function is enabled, the use of some users will be affected, light can not open some applications, prompting incompatible drivers, heavy can not compete for just started into the system.
Therefore, usually in the face of individual users, Our recommendation is not to rush to enable memory integrity protection, as this may affect your usage.
However, if you still want to try to turn on memory integrity, refer to the first link to try to identify which drivers or applications are incompatible, and try to uninstall them, remove them, or reinstall them to fix the problem.
Best regards,
Mitchell - | Microsoft community support expert from MSFT