@dirkdigs Thanks for posting in our Q&A.
For this issue, I have done a lot of research. I find that the Mobile Threat Defense partners are listed in the following link:
https://learn.microsoft.com/en-us/mem/intune/protect/mobile-threat-defense#mobile-threat-defense-partners
When we click on each partner, we will find the prerequisites about subscription. We take "Lookout for Work" as an example, it shows we need to get the following subscriptions:
For Lookout Mobile Endpoint Security enterprise subscription, it is needed to contact the 3rd party to get, and M365 doesn't provide this subscription.
Thanks for understanding.
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