Would be nice to know. Unfortunately there is no real information to be found on the net. Some says so, others so.
And at the official Microsoft documents, all of this is treated in a somewhat vague manner.
That seems to be feasible, but some things have to be modified in major way because the whole interaction between desktop application <-> Webview2 requires different techniques.
We would have liked a clearer statement from Microsoft here, especially since there are quite a few applications that have used the old web browser control element.