Hello @clint furry ,
Thanks for your query.
1.Is it working if you change the following group policy either locally or via GPO in an AD environment on all Terminal Servers/ Remote Session Hosts:
Set the following to Disabled: Computer Configuration/Policies/Admin Templates/Windows Components/Remote Desktop Services/Remote Desktop Session Host/Remote Session Environment: Use advanced RemoteFX graphics for RemoteApp – Disabled
Ensure the Remote Desktop Client on server and client are the same 'Remote Desktop Protocol' version;
Specifically, if you have a "high end" mouse, this will cause significant lag in RemoteApps. the "fix" is to downgrade your expensive mouse to a cheap one;
The fix released for the right-clicking window z-order issue of Windows 10- https://support.microsoft.com/en-us/help/4284848/windows-10-update-kb4284848
RemoteAPP after windows 10 update 1803 are slow and right mouse button is not responding (it reacts only sometimes): https://social.technet.microsoft.com/Forums/ie/en-US/f3e9852b-393c-4aa0-9d2f-961a82cfc603/remoteapp-after-windows-10-update-1803-are-slow-and-right-mouse-button-is-not-responding-it-reacts?forum=winserverTS
2.Windows 7 clients and older Windows 10 builds (1703, 1607) are working with RemoteApps normally;
To work around this problem, you can try to change the value of thepolicy Use Advanced RemoteFX graphics for RemoteApp in the local GPO editor (gpedit.msc) to the Disabled state (GPO section: Computer Configuration -> Policies -> Administrative Templates -> Windows Components -> Remote Desktop Services -> Remote Desktop Session Host -> Remote Session Environment);
To fix the problem radically, you can roll back the current Windows build to the previous version (Recovery Options -> Get Started -> Go back to the previous version of Windows 10); However, there is also a workaround, which is to replace the RDP client version with an older one.
Slow RemoteAPP Experience, Mouse and Menu Lags after Windows 10 1803 April Update: http://woshub.com/slow-remoteapp-experience-mouse-lags-windows-10-update/
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We have tried all versions of Windows server for the host 2012 through 2019, hoping that there was just a protocol mismatch (based on some discussions on other forums). Nothing other than replacing the msctax.dll and mstsc.exe with the server 2016 versions has made any impact what so ever.