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According to the error code, please try to updates available kb2975719 and kb2975331 which address this issue, depending on the Operating System.
Please refer the following link for more details:
https://blogs.technet.microsoft.com/silvana/2014/03/14/schannel-errors-on-scom-agent/
Please Note: Since the website is not hosted by Microsoft, the link may change without notice. Microsoft does not guarantee the accuracy of this information.
You can check some browsers might simply not support the required level of SSL/TLS configured on your server.
Refer the following article for more information:
https://learn.microsoft.com/zh-cn/archive/blogs/kaushal/ssltls-alert-protocol-the-alert-codes
If the problem still unsolved, it is recommended to have this asked in AD forum for better answers.
AD forum: https://social.technet.microsoft.com/Forums/en-US/home?forum=winserverDS
About event ID:10016,these events can be safely ignored because they do not adversely affect functionality and are by design.
Please refer the following link:
https://support.microsoft.com/en-us/help/4022522/dcom-event-id-10016-is-logged-in-windows
Best Regards,
Candy