Hi,
Welcome to ask here!
Before any configuration, it is suggested to fix the issues on the DC.
Run command on all DCs.
ipconfig /all > C:\dc.txt
Dcdiag /v >c:\dcdiag1.log
Repadmin /showrepl >C:\repl.txt
Repadmin /showrepl *
repadmin /showrepl /all >c:\repadmin.txt (Inbound and outbound replication for one single DC)
Repadmin /syncall /APeD
After the fixing the errors on DC , we can try to configure the Home Profile again.
a, Create a shared folder for users, configure share permission for users as following:
Administrators: Full Control
System: Full Control
Authenticated Users: Full Control
b, Configure NTFS permission for users.
c, The UNC path should be:xt box area
\servername\sharename\%username%
For more details, you can refer to the following link
https://techcommunity.microsoft.com/t5/ask-the-directory-services-team/automatic-creation-of-user-folders-for-home-roaming-profile-and/ba-p/395527